儿科感染常见病原菌及其耐药性分析

Analysis on Frequency and Drug-resistance of Bacterial Pathogens in Pediatrics

目的了解儿科感染常见的病原菌及其耐药性,为合理用药提供依据。方法用微生物检验常规方法培养、分离、鉴定病原菌,药敏试验用纸片扩散法。结果儿科感染最常见的前5位病原菌依次为凝固酶阴性葡萄球菌(占16.8%)、大肠埃希菌(占13.8%)、金葡菌(占12.6%)、克雷伯菌属(占10.9%)和志贺菌属(占8.9%);55.3%的葡萄球菌对苯唑西林耐药,万古霉素是革兰阳性菌最为敏感的抗生素,大多数革兰阴性杆菌对亚胺培南、第三代头孢菌素敏感。结论应重视儿科的细菌耐药性监测,随时掌握细菌耐药动态。

Objective To investigate the common pathogenic bacteria and their drug-resistance in pediatric infection.~Methods Bacteria were detected by routine microorganism tests, and drug-resistance was tested by disk diffusion method.~Results The five most frequently isolated becteria were coagulase-negative staphylococci (16.8%)、escherichia coli (13.8%)、staphylococcus aureus (12.6%)、klebsiella sp. (10.9%) and shigella sp. (8.9%). The drug-resistant rate against oxacillin in staphylococci was 55.3%. The vancomycin was the most effective antibiotics against gram-positive organisms. Most of the gram-negative bacilli were sensitive to imipenem、third-generation cephalosporins.Conclusion Constant surveillance of microbial pathogens and drug-resistance strains in pediatrics is essential.