脑梗死患者红细胞胆固醇含量检测及临床意义

Measurement or Erythrocyte Cholesterol Contents of Cerebral Infarction Patients and Its Clinical Significance

检测了42例脑梗死急性期患者和64例年龄相匹配的健康成人的红细胞胆固醇（E－Ch）含量。采用的方法是单一试剂异丙醇抽提和胆固醇酶联试剂显色法。结果表明，患者组E－Ch的含量明显比对照组E－Ch含量高（P＜0．001）。提示脑梗死急性期患者红细胞膜内脂质代谢呈现紊乱异常，E－Ch含量可作为辅助诊断动脉粥样硬化和脑梗死的一项参者指标。

The results of measuring erythrocyte cholesterol (E－Ch) contents of 42 acute cerebralinfarction patients and 64 healthy adults with the single reagent isopropanol extract andcholesterol enzyme linked reagent deveIopment process showed that the average E－Ch contents of the patient group was significantly higher than that of the control group (P<0.001). It suggested that there were disorder and abnormality in lipid met abolism in theerythroccyte membrane of the acute cerebral infarction patient. The measurement of E－Chcontent may be used as a criterium in the diagnoses of atheroslerosis and cerebral infarction.