老年人肺部感染与多器官功能衰竭116例临床分析

Pulmonary Infection and MOF in the Elderly (A Clinical Analysis of 116 Cases)

分析116例老年人以感染为主要诱发因素的多器官衰竭（MOF）的临床资料，发现由肺部感染所诱发的MOF居首位，占81．0％，细菌学检查以革兰氏阴性杆菌居多。多器官衰竭的先后顺序为：肺、心、脑、肾、肝。2～4个器官衰竭者病死率为51．9％～83．3％，5个以上器官衰竭者13例，全部死亡，病死率100％。提示老年人各器官功能不全，免疫功能低下是MOF的主要因素，肺部感染为始动因素。并对其预后及诊治中的经验教训进行了讨论。

One hundred and sixteen cases of MOF above 60 years of age were restrospectively analysed. All of them were induced by infection, with pulmonary infection as the main precipitating factor (81. 0% ). Among them, gram negative bacilli were the most common. The sequence of failured organ was lungs, heart,brain, kidneys and liver. The mortality of the patients with failure of 2-4 organs was 51. 9%-83. 3% and 5 organs was 100%. The paper implies that the functional insufficiency of multiple organs and immunodeficiency are the main factors, and pulmonary infection is often the initiative cause. The prognosis and other related factors of MOF in the elderly were also discussed.