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浆细胞样树突状细胞研究进展 被引量:3

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摘要 浆细胞样树突状细胞(pDC)是一类近年来被认识并被证明在免疫应答与免疫耐受中发挥重要作用的免疫细胞,其最突出的功能特点是在病毒、CPG ODN的刺激下产生大量的Ⅰ型干扰素,因此又被称为是天然Ⅰ型干扰素产生细胞(IPC)。由于其在来源、表型等方面都与我们以前所熟知的髓系树突状细胞有着很大的差异并具备独特的功能而引起广泛的关注。本文综述了pDC的来源、表型、功能特点,包括对T细胞的诱导分化及其与疾病的关系等方面的研究进展。
出处 《国外医学(免疫学分册)》 2005年第4期204-209,共6页 Foreign Medical Sciences(Section of Immunology Foreign Medical Sciences)
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  • 1Blom B, Ho S, Antonenko S, et al. Generation of interferon alpha-prnducing predendritic cell (pre-DC)2 from human CD34(+) hematopoietic stem cells[J].J Exp Med,2000,192(12): 1785-1796.
  • 2Spits H, Couwenberg F, Bakker AQ, et al. Id2 and Id3 inhibit development of CDM(+) stem cells into predendritic cell (pre-DC)2 but not into pre-DC1. Evidence for a lymphoid origin of pre-DC2[J].J Exp Med,2000,192(12): 1775-1784.
  • 3Weijer K, Uittenbogaart CH, Voordouw A, et al. Intrathy-mic and extrathymic development of human plasmacytoid dendritic cell precursors in vivo[J]. Blood,2002,99(8):2752-2759.
  • 4Rissoan MC, Duhen T, Bfidon JM, et al. Subtractive hybridization reveals the expression of immunoglobulin-like trasncript 7, Eph-B1, granzyme B,and three novel transcripts in human plasmacytoid dendritic cells [J].Blood, 2002,100(9):3295-3303.
  • 5Schotte R, Rissoan MC, Bendfiss-Vermare N, et al.The transcription factor Spi-B is expm.s,sed in plasmacytoid DC precursors and inhibits T, B and NK cell development[J]. Blood, 2003,101(3): 1015-1023.
  • 6Bianea B, Suzanne J, Schotte R, et al. Developmental origin of Pre-DC2[J]. Hum Immunol,2002,63(12):1072-1080.
  • 7Ito T, Inaba M,Inaba K,et al.A CD1a^+/CD11c^+ subset of human blood dendritic cells is a direct precursor of Langerhans cells[J]. J Immunol,1999,163(3):1409-1419.
  • 8Belmont HM, Buyon J, Giomo R, et al. Upregulation of endothelial cell adhesion molecules characterizes disease activity in systemic lupus erythematosus. The Shwartzman phenomenon revisited[J]. Arthritis Rheum, 1994,37(3):376-383.
  • 9Vanbervliet B, Bendriss-Vermare N, Massacfier C, et al. The inducible CXCR3 ligands control plasmacytoid dendritic cell responsiveness to the constitutive chemokine stromal cell-derived factor 1(SDF-1)/CXCL12 [J]. J Exp Med,2003,198(5):823-830.
  • 10Hemmi H, Kaisho T, Takeuchi O, et al. Small anti-viral corrgaounds activate immune cells via TLR7-MyD88-dependent signaling pathway[J]. Nat Immunol,2002,3(2):196-200.

同被引文献33

  • 1张永亮,曹雪涛.浆细胞样树突状细胞免疫调节功能研究进展[J].现代免疫学,2005,25(2):167-170. 被引量:3
  • 2焉传祝,李大年.多发性肌炎/皮肌炎的组织病理定量研究和超微…[J].中华神经精神科杂志,1994,27(3):141-145. 被引量:7
  • 3吕毅,赵淑华,杨湘山.双酚A对妊娠小鼠仔鼠免疫功能影响[J].中国公共卫生,2006,22(12):1534-1534. 被引量:5
  • 4Dalakas MC,Hohlfeld R.Polymyositis and dermatomyositis.Lancet,2003,362:971-982.
  • 5Dalakas MC.Polymyositis,dermatomyositis and inclusion-body myositis.N Engl J Med,1991,325:1487-1498.
  • 6Dalakas MC.Muscle biopsy findings in inflammatory myopathies.Rheum Dis Clin North Am,2002,28:779-798.
  • 7Beilke MA,Traina-Dorge V,England JD,et al.Polymyositis,arthritis and uveitis in a macaque experimentally infected with human T lymphotropic virus type Ⅰ.Arthitis Rheum,1996,39:610-614.
  • 8Dalakas MC.Immunopathogenesis of inflammatory myopathies.Ann Neurol,1995,37 Suppl 1:S74-86.
  • 9Greenberg SA.Proposed immunologic models of the inflammatory myopathies and potential therapeutic implications.Neurology,2007,69:2008-2019.
  • 10Karpati G,Carpenter S,Melmed C,et al.Experimental ischemic myopathy.J Neurol Sci,1974,23:129-161.

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