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mta1/MTA1在乳腺癌转移过程中的作用及可能机制 被引量:5

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摘要 mta1是一个肿瘤转移相关基因其蛋白表达水平与人及鼠乳腺癌细胞株的转移能力成正相关。此蛋白一方面可能通过参与信号转导,调控一系列与浸润转移有关的蛋白;另一方面MTA1蛋白定位于核内,通过与组蛋白去乙酰化酶结合,影响组蛋白乙酰化水平,进而参与乳腺癌转移过程。
作者 杜媛媛 张徽
出处 《国外医学(生理病理科学与临床分册)》 2005年第3期260-263,共4页 Foreign Medical Sciences(Pathophysiology and Clinical Medicine)
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同被引文献32

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