高能聚焦超声治疗良性前列腺增生的初步研究

A preliminary study on the efficacy of focused ultrasound surgery for the treatment of benign prostatic hyperplasia

目的评价高能聚焦超声(FUS)治疗良性前列腺增生(BPH)的临床疗效。方法应用FEPBY01聚焦超声热疗仪对32例BPH患者行FUS治疗,治疗前及治疗后1个月填写国际前列腺症状评分表(IPSS),进行直肠指诊、B超及尿流率等检查,比较治疗前后的差异。结果与治疗前相比,治疗后IPSS均值由21.2±5.3降为18.6±5.3,降低12.3%;前列腺体积均值由治疗前的60.1±36.8变为51.2±32.4,缩小14.8%;最大尿流率均值由治疗前5.9±1.5升至8.72±2.1,提高48.0%。治疗前后比较差异有显著性。结论FUS短期内能改善BPH症状,缩小前列腺体积,提高最大尿流率。

Objective To conduct a preliminary study on the efficacy of focused ultrasound surgery (FUS) in treatment of benign prostatic hyperplasia (BPH).Methods Thirty-two patients underwent FUS with FEP-BY01 instrument.International Prostate Symptom Score (IPSS), digital rectal examination, ultrasonography and uroflometry were done before operation and one month after operation.Results After operation the mean IPSS decreased from 21.2±5.3 to 18.6±5.3,with a decrease rate of 12.3%,the mean volume of the prostate reduced from 60.1±36.8 to 51.2±~32.4 ,with a reduction rate of 14.8%,and the mean maximum flow rate increased from 5.9±1.5 to 8.72±2.1,with an increase rate of 48.0%. There were significant differences between pre-and post-treatment.Conclusion FUS can improve the BPH symptoms, reduce the prostate volume and increase the maximum flow rate of urine.