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四氢生物蝶呤与内皮细胞功能障碍 被引量：1

The Relationship Between Tetrahydrobiopterin and Endothelial Dysfunction
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摘要 许多心血管疾病中存在血管内皮细胞功能异常,其机制可能为内皮细胞生成的一氧化氮(NO)活性降低,四氢生物蝶呤(BH4)是一氧化氮合酶(NOS)的辅因子,该辅因子有调节NOS功能和NO活性的作用,本文就BH4在心血管疾病中的研究作一综述。 Endothelial function disorder exists in many cardiovascular diseases,which may come from the decrement of nitric oxide.Tetrahydrobiopterin is a kind of essential cofactor of nitric oxide synthase,which can regulate nitric oxide synthase function and activity of nitric oxide.This article reviews the usefulness of tetrahydrobiopterin in cardiovascular diseases.
作者 张艳青 李著华
机构地区 扬州大学医学院病理生理教研室 泸州医学院病理生理教研室
出处 《心血管病学进展》 CAS 2005年第4期436-439,共4页 Advances in Cardiovascular Diseases
关键词 四氢生物蝶呤 内皮功能 一氧化氮 Tetrahydrobiopterin Endothelial function Nitric oxide
分类号 R54 [医药卫生—心血管疾病]
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参考文献23

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同被引文献10

  • 1刘秀华,唐朝枢.缺血再灌注损伤的防治——从实验室到临床[J].中华心血管病杂志,2006,34(8):677-679. 被引量：33
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  • 6Laskey WK. Brief repetitive balloon Occlusions enhance reperfusion during percutaneous coronary intervention for acute myocardial infarction: a pilot study. Catheter Cardiovasc lnterv, 2005,65 : 361-367.
  • 7Zhi-Qing Zhao. Oxidative stress-elicited myocardial apoptosis during reperfusion. Current Opinion in Pharmacology,2004, 4:159 165.
  • 8A. Valtchanova-Matchouganska, M. Gondwe, A. Nadar. The role of C-reactive protein in ischemia/reperfusion injury and preconditioning in a rat model of myocardial infarction. Life Sciences,2004, 75 : 901 -910.
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心血管病学进展
2005年 第4期

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