白内障超声乳化吸出术后多焦视网膜电图变化

Multifocal electroretinogram in cataract patients after phacoemulsification

目的:采用多焦视网膜电图(multifocalelec-troretignroam,mfERG)评价年龄相关性白内障患者行超声乳化白内障吸出术后视网膜功能的改变。方法:应用法国Metrovision公司生产的VisionMonitor视觉诱发系统检测23例23眼年龄相关性白内障超声乳化术后及8例11眼同龄正常对照眼的mfERG,检测视野的水平视角±30°,垂直视角±23°,采用ERG-jet接触镜电极,于5min记录61个视网膜部位的反应。结果:与正常对照组比较,白内障术后组mfERG的N1波潜伏期在各视网膜半区、4个象限及第2～5环延长,差异有显著性意义;P1波潜伏期在视网膜上半区、颞侧区、颞上象限、颞下象限和第2～4环延长,差异有显著性意义;N2波潜伏期在视网膜下半区、颞下象限及第2～4环明显延长,差异亦有显著性意义。术后组N2波振幅密度在视网膜颞侧区、颞上和颞下象限降低,与对照组比较差异有显著性意义。结论:白内障术后眼mfERG的一阶kernal反应有明显改变,为进一步研究白内障患者视网膜的功能提供参考。

· AIM: To evaluate the alteration of the retinal function in age-related cataract patients after phacoemulsification by using multifocal electroretinogram (mfERG).· METHODS: The mfERG by using Vision Monitor visual evoked response imaging system was tested in 23 cases (23 eyes) with age-related cataract after phacoemulsification and 8 cases (11 eyes) of normal subjects. The stimulative visual angles were subtended±30° horizontally and ±23° vertically. ERG-jet contact lens electrode was used to record the response from 61 retinal locations in 5min.· RESULTS: Compared with the Normal Subjects, the latencies of N1 wave of the Operative Group at the 4 half retinas, and the 4 quadrants as well as the 2nd-5th ring significantly delayed. The latencies of P1 wave of the Operative Group at the upper and the temporal retinas, the superior temporal and the inferior temporal quadrants, as well as the 2nd-4th ring were longer than those of the Normal Group. The latencies of N2 wave of the Operative Group at the lower retinal, the inferior temporal quadrant and the 2nd-4th ring were longer than those of the Normal Group. The amplitude densities of N2 wave of the Operative Group at the temporal retina, the superior temporal and the inferior temporal quadrants decreased. There were statistically significant differences between the 2 groups.· CONCLUSION: The kernel response of mfERG of cataract patient after the operation has obvious alteration, and can provide references to study the retinal function of cataract patients.·