摘要
目的:观察糖尿病性视网膜病变(DR)各期病程改变及进行危险因素分析。方法:单纯性I,II,III期170例290眼。单纯型进展为增殖型糖尿病视网膜病变(PDR)IV期,随访2a为42眼14%,5a为98眼34%。结果:I,II,III进展至IV期的发生率:III期>II期,II期>I期,差别均有显著性(P<0.05)。糖尿病黄斑水肿随随访年限增长而增加,初诊黄斑水肿70眼,2a内增至86眼,5a内增至110眼。视网膜静脉串珠状改变,视网膜内大量微血管异常和4个象限内存在出血和/或微血管瘤是单纯型进展至PDR的危险性病变。血糖控制不良,糖尿病病程长和高血压可能是单纯型进展至PDR的危险因素。结论:为预防或减少DR致盲,应早期发现DR,并给予长期随访。
· AIM: To study the clinical manifestation and risk factors of diabetic retinopathy.· METHODS: A total of 170 cases (290 eyes) with stage I II III diabetic retinopathy were included in this study. Forty-two eyes (14%) developed stage IV within 2a and 98 eyes (34%) developed stage IV within 5a.· RESULTS: The occurrences of different stages of nonproliferative diabetic retinopathy evolving into stage IV were different: III>II, II>I (P <0.05). The incidence of diabetic macular edema increased as time passed. There were 70 cases with diabetic macular edema at first visit, 86 eyes within 2a and 110 eyes within 5a. The risk factors of proliferative diabetic retinopathy were pearl-like changes of retinal veins, a lot of abnormal retinal capillaries and microaneurysm or bleeding in 4 quadrants. Unstable blood glucose level, long history of diabetes mellitus and hypertention might be the risks factor of proliferative diabetic retinopathy. · CONCLUSION: Early diagnosis and follow-up are important for the prevention of proliferative diabetic retinopathy. ·
出处
《国际眼科杂志》
CAS
2005年第3期578-580,共3页
International Eye Science
