HAV、HBV重叠感染34例分析

ANALYSES OF 34 CASES IN OVERLAPPINGINFECTIONS OF HAV AND HBV

本文回顾了３４例ＨＡＶ和ＨＢＶ重叠感染者的临床经过和ＨＢＶ血清标志物改变。发现其甲肝的整个临床过程基本与一般甲肝一致；与ＨＡＶ感染前比较，ＨＡＶ感染恢复后１～２个月时ＨＢＶ血清标志物的阳性率（除ＨＢｓＡｇ和拉ＨＢｓ外）发生了明显改变：ＨＢｅＡｇ由７５％减至３５．３％，拉ＨＢｃ由８５．７％减至４１．２％，三项阳性者由６４．３％减至３５．３％，拉ＨＢｅ由３９．３％增至７６．５％，拉ＨＢｃ－ＩｇＭ由５４．３％减至２６．５％（均为Ｐ＜０．０１）。

The article reviewed the clinical courses and changes of HBV serologicmarks of 34 patients in overlapping infections of HAV and HBV. We found thatwhole clinical courses of the hepatitis A were essentially similar with common hepatitis A; and compared with those before HAV infections, after HAV infections had recovered for 1-2 months, the positive percentages of HBV serologic marks (exceptHBsAg and anti-HBs) changed much: HBeAg from 75% to 35. 3%, anti-HBcfrom 85.75% to 41.2%, the three positive from 64.3% ti 35.3%, anti-HBe from39.3% to 76.5%, anti-HBc-IgM from 54. 3% to 26.5% (P<0. 01 in all).