残胃近期及远期粘膜病变的对比观察

A comparative study on short-and long-term mucosal changes of gastric stump

本文观察了８６例残胃粘膜病变的病理形态特征。该病变是一种以粘膜上皮和腺体活跃增生为主的病变，不同于一般慢性萎缩性胃炎和慢性浅表性胃炎。该病变在胃术后近期（４～６个月）即可出现，大部分持续到远期（数年到３３年）不变，少部分加重或癌变。其形成因素有多种，根据病变特点，我们认为十二指肠反流液和化学刺激是重要因素。

The pathological features of mucosal changes in the gastric stumps(MCGS) of 86 cases were reported.The active proliferation of mucosal epithelial cells and glands of the stump was the main finding, being different from the changes in chronic atrophic gastritis and chronic superficial gastritis. MCGS occurred in 4 to 6 months after gastrectomy and most of the disease persisted over several to 33 years without changes,but the disease was aggravated or cancered in a few cases. Many factors may be attributed to be tha causes of MCGS. It is believed that the duodenal fluid reflux and chemical irritation play important roles in the causation of MCGS.