血管闭合装置在经皮冠状动脉成形术后的应用

Haemostatic closure device(per-close) after cardiac catheterization

目的比较心血管病患者经皮冠状动脉成形术(PCI)后采用经皮血管闭合装置(per-close)止血与人工压迫止血的安全性和疗效。方法280例心血管病患者在行经皮冠状动脉成形术后,分为人工压迫止血组(145例)和per-close止血组(135例),观察2组止血时间、下床活动时间、术后血管并发症等。结果止血组与人工压迫组相比,止血时间与下床活动时间显著缩短,血管并发症明显减少。应用per-close的成功率达95%。结论此研究显示,PCI术后应用经皮血管闭合装置,是一个快速、有效的止血方法,缩短了止血与下床活动时间,并可减少穿刺点并发症发生率及患者不适感。

Objective To assess the safety and efficacy of suture-mediated closure device(per-close) in patients after cardiac catheterization procedures. Methods 280 consecutive patients who underwent cardiac catheterization procedures were divided into manual compression groug(145 case) and per-close groug(135 case) .The time to hemostasis,time to ambulation and vascular complications were compared between the two groups. Results A significant reduction in time to achieve hemostasis and time to ambulation was associated with use of the per-close decvice. The incidences of vascular complications occurrence rate were downtrend in per-close groups. The successful hemostasis rate by per-close device was 95%. Conclusion The study demonstrates that hemostasis with per-close device after percutaneous coronary intervention is a very fast and effective method, it can be safely and efficacy utilized to achieve hemostasis afrer femoral artery access in percutaneous coronary intervention.