摘要
24例髓母细胞瘤分成儿童组和成人组,进行病理形态观察和DNA含量分析。两组肿瘤的病理类型、菊形团、器官样结构及细胞分化等项无统计学差别,但儿童组的肿瘤坏死比成人组者明显增多。DNA分析观察到儿童组的异倍体率、细胞周期动力学和细胞增殖指数(PI)均比成人组增高,此结果提示儿童组髓母细胞瘤比成人组者对放射治疗的敏感性较高。
Clinico-pathomophological investigation and DNA content analysis. In 24 cases of medulloblastoma including children group and adults,There were no statistical differentiation in pathological types, rosseles, organoid structures and cell differentiation, but tumor neoro-sis. The cell cycle dynamics and cellular proliferative index were higher in children than in adultse, These results suggest that the medulloblastomas of the children group have higher sensitivity for the radio-therapy than that of the adults group.
出处
《临床神经科学》
1994年第1期8-10,共3页
Chinese Journal of Clinical Neurosciences
