摘要
目的研究亚低温对急性重型颅脑损伤患者颅内压及脑温的影响。方法选择52例急性重型颅脑损伤患者进行颅内压及脑温监测的同时,将患者随机分为亚低温组和对照组进行研究。结果亚低温组颅内压降低。伤后早期脑温比肛温高,但二者均高于正常值,在亚低温治疗过程中脑温和肛温均下降,但二者的差距逐渐增大,有显著性差异(P<0.05)。亚低温组病人死亡率低于对照组,而恢复良好率显著高于对照组(P<0.05)。结论亚低温能降低颅内压及脑温,改善预后。
Objective To study the effect of mild hypothermia for ICP and BT in patients with severe head injury.Methods 52 patients with severe head injury were divided into mild hypothermia group and control group by random,and all patients were monitored ICP(intracranial pressure) and BT(brain temperature).Results The mild hypothermia therapy lower ICP.BT was higher than RT (rectal temperature) after injure,but both BT and RT were higher than normal temperature.The BT and RT were decreased when the patients were treated with mild hypothermia,but at the same time the difference between the BT and RT was increased(P<0.05).The death rate of mild hypothermia group was lower than that of control group,and the good recover rate of mild hypothermia group was higher than that of control group(P<0.05).Conclusion The mild hypothermia therapy could lower ICP and BT,and improve the prognosis.
基金
广东省深圳市科技计划项目(编号:深科信〔2004〕164号-200405070)