摘要
目的观察胞二磷胆碱联合灯盏花素治疗椎基底动脉供血不足性眩晕的疗效。方法给予胞二磷胆碱0.5g静滴,1次/d,连用14d;灯盏花素100mg静滴,1次/d,连用14d。观察治疗前后血脂、血液流变学、临床症状的变化。结果治疗后总胆固醇(TC)、甘油三脂(TG)较治疗前明显降低(P<0.01,P<0.05);治疗后全血粘度、血浆比粘度、红细胞聚集指数及红细胞变形能力均有明显改善(均P<0.01);治疗后眩晕明显好转,68例眩晕缓解,6例仍存轻度头晕。结论胞二磷胆碱联合灯盏花素治疗椎基底动脉供血不足性眩晕疗效较好,无不良反应。
Objective To observe the curative effect of treatment of giddiness from insufficient vertebra artery blood supply by using citicoline breviscapine. Methods Intravenous drip infusion of 0.5g citicoline and 100mg breviscapine,1 time per day consecutively for 14 days.The change of blood fat,blood flow and clinical symptoms prior and after the treatment was observed. Results There was an obvious drop in TC and TG after the treatment,comparing with the figures prior the treatment ((P<0.01,P<0.05)).There was also a significant improvement on whole blood viscosity,blood plasma ratio viscosity,red blood cell aggregation index as well as red blood cell deformation (average P<0.01).After the therapy,the giddiness took an obvious turn for the better with 68 cases of giddiness relieved and 6 cases remained slight giddy.Conclusion A satisfactory curative effect is obtained by using citicoline and breviscapine to treat the giddiness caused by insufficient vertebra basilar artery blood supply and no adverse effect is found.
