羊水偏少与围产儿结局的临床研究

Clinecal study of adverse perinatal outcome for a borderline amniotic fluid index.

目的探讨羊水偏少孕妇发生胎儿不良结局的危险。方法2002年8月～2002年12月在四川省人民医院产科住院分娩的产妇202例,羊水指数(AFI)测量8.1～20cm为羊水量正常,5.1～8.0cm为羊水偏少。围产儿不良结局包括胎儿宫内窘迫、5分钟Apgar评分≤7、胎儿生长受限(FGR)、死胎、胎儿畸形发生率。结果围产儿不良结局的发生率羊水偏少组较正常组发生率增高,FGR发生率较正常组增加两倍。结论产前检查羊水偏少患者发生围产儿不良结局及FGR的风险增高。

Objective: Our purpose was to determine whether a borderline amniotic fluid index confers a significant risk of adverse perinatal outcome. Methods: We conducted a retrospective review of all patients entering antepartum testing at the people's hospital of Sichuan province during a 4-month period beginning Augest 2002. An amniotic fluid index >5 and <8 cm was defined as 'borderline' and an amniotic fluid index of 8.1 to 20 cm was considered normal. Markers of adverse perinatal outcome included intrapartum fetal distress, 5-minute Apgar score<7, and fetal growth restriction,fetal death and fetal abnormality. Results: There was a increase in the incidence of adverse perinatal outcome among the women with borderline amniotic fluid index in comparison with control subjects with normal amniotic fluid volume. and a 2-fold increase in the incidence of fetal growth restriction among women with a borderline amniotic fluid index. Conclusion: A borderline amniotic fluid index observed in antepartum testing is associated with an increased risk of fetal growth restriction and overall adverse perinatal outcome.