甲状腺功能减退性肌病误诊为多发性肌炎10例分析

Hypothyroid myopathy misdiagnosed as polymositis

目的探讨甲状腺功能减退性肌病与多发性肌炎容易误诊的原因。方法回顾分析10例甲状腺功能减退性肌病患者的临床表现及实验室检查资料,并复习有关文献。结果甲状腺功能减退性肌病与多发性肌炎在肌肉方面的表现相似,但甲状腺功能检查可以鉴别,左甲状腺素替代治疗有效。结论对于肌肉无力和肌酶升高者需常规检测甲状腺功能。

Objective To analyze hypothyroid myopathy that were misdiagnoed as polymyositis. Methods The clinical manifestations and laboratory parameters of 10 patents with hypothyroid myopathy were analyzed and the relevant literature were reviewed. Results Hypothyroid myopathy and polymyositis had similar symptoms of muscle dysfunction and elevation of serum muscle enzymes, but could be distinguished by thyroid function tests. Replacement therapy with levothyroxine was effective. Conclusions Thyroid function tests should be routinely examined in all patients with muscle weakness or elevation of muscle enzymes.