超声组织定征对慢性乙型肝炎病理肝脏炎性程度的测量研究

Measurement study on hepatic inflammation changes of patients with chronic hepatitis Busing ultrasound tissue characterization

目的探讨超声组织定征(UTC)对慢性乙型肝炎肝脏炎性病变不同程度进行量化诊断的作用。方法用UTC视频法测量慢性乙型肝炎患者二维超声图像的灰阶值,并与其肝穿病理组织学肝脏炎性病变分级对比。结果UTC视频法测出的肝脏声像图的灰阶值在慢性乙型肝炎病理组织学肝脏炎性病变分级中的差异有统计学意义(P<0.01)。肝脏炎性病变分级G0、G1、G2和G3各组间灰阶值的差异均有显著意义(P<0.05)。结论可用超声视频法这一无创性的检查方法对慢性乙型肝炎肝脏炎性病变的程度进行声像图量化诊断。

Objective To study a kind of quantitative diagnosis method with ultrasound tissue characterization on hepatic inflammation changes of the patients with chronic hepatitis B.Methods Measured the gray scales of the two dimensional ultrasongraphy of the patients and compared the gray scales with the inflammation changes on histopathology of the patients and found the differences between every two groups.Results The differences of the gray scales compared with the inflammation changes on histopathology are meaningful on statistics(P<0.01) and the gray scale differences among groups are all remarkable(P<0.05).Conclusion The quantitative diagnosis of the hepatic inflammation changes of the patients suffering from chronic hepatitis B can be acquired through measuring the gray scales of the two dimensional ultrasongraphy of the patients.