多指标联合检测在良恶性胸水中的诊断价值

The Value of ADA,CEA and Fer in the Differential Diagnosis of Malignant and Tuberculous Pleural Effusion

目的探讨腺苷脱氨酶(ADA)、癌胚抗原(CEA)和铁蛋白(Fer)对结核性和癌性胸水的诊断价值。方法检测36例结核性胸膜炎和38例癌性患者胸水中的ADA、CEA和Fer含量。结果Fer、ADA、CEA单项检测的诊断准确性分别为80%、83%、82%;三项联合检测其中二项或三项同时阳性的诊断准确性分别为90%、91%、89%、93%。结论胸液Fer、ADA、CEA联合检测可提高胸水良恶性鉴别诊断的准确性。

Objective To investigate the value of ADA,CEA and Fer in the differential diagnosis of malignant and tuberculous pleural effusion.Methods The activity of ADA,CEA and Fer was tested in 36 patients with tuberculous pleural effusion and in 38 patients with malignant pleural effusion.Results the diagnostic accuracy of Fer,ADA and CEA was 80%, 83% and 82% respectively when they were used alone to examine pleural effusion and the diagnostic accuracy would the increased when 2 of them or all the 3 were used simultaneously to examine pleural effusion.Conclusion The combined application of Fer, ADA and CEA improves the accuracy of differential diagnosis of pleural effusion.