脑外伤后综合征的SPECT显像初步观察

PRELIMINARY STUDY ON THE HEAD-INJURY BY USING SPECT WITH ￣(99m)TcHMPAO

脑外伤后综合征发病机理尚不十分清楚．本研究通过４２例临床诊断为脑外伤后综合征患者的脑ＳＰＥＣＴ显像和其他辅助诊断技术及病理资料等，探讨其发病机理．结果发现４２例患者中有３３例ＳＰＥＣＴ显像呈异常表现，占７８．６％．３３例脑ＳＰＥＣＴ显像异常患者中１３例呈多发性放射性减低灶．这提示脑外伤后综合征的发病有其病理、生理基础，而且和脑血流灌注关系密切．并且提示脑外伤后．脑实质的损害还有可能为弥漫性的，并不完全局限于受伤部位．从病程分组的结果看，脑外伤的血流改变和病程长短的关系并不大．通过上面的观察，可以解释部分脑外伤后综合征的发病机理，并且同时为临床上的鉴别诊断和指导治疗方面提供有价值的资料．

Abstract After the acute period of head truama, some cases of patients may have some symptoms, such as headache, poor memory, vertigo, et al. In this study, among 42 patients most of whom had normal CT or MRI abnormal findings of brain perfusion imaging were seen in 33 patients (78.6%). Multiple perfusion defects were observed in some patients (13/42). These indicate that the head-injury syndrome is closely related to brain blood perfusion. Our conclusion is that the brain SPECT is able to find out the etiology of head injury syndrome.