放射性核素肺断层显像预测残留肺功能的应用研究

THE STUDY OF RADIONUCLIDE LUNG SPECT IMAGING FOR THE PREDICTION OF RESIDUAL LUNG FUNCTION

应用放射性核素肺断层显像预测肺切除术后的残留肺的肺功能状态．１４０例均经手术或病理证实，其中原发性肺癌１２７例，良性病变１１例和转移性肺癌２例．对８７例肺部手术病人的呼气容积预测值和手术后的实测值、４０例肺叶切除病人的手术前后Ｑ值进行了对比分析，均示显著相关，前者Ｐ＞０．０５，ｒ＝０．９９２５，后者Ｐ＞０．０５，ｒ＝０．８６５．文中描述了残留肺功能预测的公式推导和计算方法，并就断层显像方法学的优点和正确性，临床应用的可靠性以及预测呼气容量的手术临界值等问题进行了讨论．认为本方法为可靠和实用的无创性方法，有临床实用价值．

Abstract This article reported the prediction of residual lung function before pulmonary lobectomy by the method of radionuclide lung perfusion tomographic study. 140 cases of pulmonary diseases were proved by pathologic section or operation. Among them, there were 127 primary lung cancers, 11 benign lesions and 2 metastatic lung cancers. Comparative analyses were performed between the predicted expiratory volume (PFEV1) and the actual measured volume (FEV1) after operation in 87 cases of pulmonary lobectomy, and also the Q value before and after operation in 40 cases with pulmonary lobectomy. All showed significantly correlated results, P>0.05, r=0.9925 in the former group and P>0.05, r= 0.865 in the latter group. The derivation of the formula and the method of calculation for the prediction of residual pulmonary function were described.