涎腺多形性腺瘤中肌上皮细胞的免疫电镜研究

An immunoelectron microscopic study of the myo-epitbelial cells in salivary gland pleomorphic adeno-ma

采用抗肌动蛋白（ａｃｔｉｎ）、抗肌球蛋白（ｍｙｏｓｉｎ）、抗Ｓ－１００蛋白、抗胶质纤维酸性蛋白（ＧＦＡＰ）和抗波形蛋白（ｖｉｍｅｎｔｉｎ）抗体对５例腮腺多形性腺瘤中肿瘤性肌上皮细胞进行标记，发现该瘤的肿瘤性肌上皮细胞形态变化大，分布范围广，是该瘤主要增生的肿瘤细胞。在粘液样区域中，部分肿瘤性肌上皮细胞出现早期软骨样分化的特征。提示它在该瘤组织发生中起着重要作用。

AbstractIn the present study,the neoplastic myoepithe-lial cells in five pleomorphic adenomas of parotidgland were labeled with actin, myosin, S-100 pro-tein, glial fibrillary acidic protein (GFAP) and vi-mentin. We have found that the neoplastic myoep-ithelial eells have many different morphologic fea-tures, they are the principal proliferating cells in thetumors. In the myxoid region, part of the neoplasticmyoepithelial cells have early chondroid differentiation, this shows that the neoplastic myoepithelialcells take the important role in the histogenesis of thetumors.