结核分枝杆菌初始耐药监测分析报告

The Analysis of Drug Resistance of Tuberculosis Mycobacterium

目的:监测结核分枝杆菌的耐药情况,评价江门市结核病控制工作成效。方法:对2000年至2004年我市结核病人痰培养阳性菌株进行初始耐药性监测。结果:初治1075例痰培养阳性结核分枝杆菌,有150例耐药,初始耐药率为13.95%,耐1药和2药率分别占耐药总数的44.7%和36.0%,耐3药4药率共占耐药总数的19.3%,2004年比2000年初始耐药率下降幅度54.7%。结论:连续观察5a江门市结核分枝杆菌初始耐药率呈逐年下降趋势,提示耐药结核病的流行状况已有好转,结核病控制工作取得明显效果。

Objective To surveil the condition of tuberculosis my cobacterium and to evaluate the work of controlling tuberculosis in Jiangmen.Method To surveil the drug resistance of the positive bacteria grown by the phlegm of the tuberculosis patients in our city from 2000 to 2004.Results In the treatment of 1 075 cases of positive tuberculosis my cobacterium grown from the phlegm,150 cases reveal drug resistance,the percentage of the first drug resistance is 13.95%,the percentage of 1-resistance and 2-resistance is 44.7% and 36.0% respectively,the percentage of 3-resistance and 4-resistance is 19.3% totally,and the percentage of drug resistance in 2004 is 54.7% lower than that in 2000.Conclusion The observation of the downtrend of drug resistance of tuberculosis my cobacterium in the consecutive five year in Jiangmen, shows that the epidemic condition of drug-resistant tuberculosis has been improved and the work of controlling tuberculosis has got a good result.