肾综合征出血热并发中枢神经系统损伤的心电图分析

Analysis of cardiogram of patients with hemorrhagic fever with renal syndrome complicating nervous system injury

目的探讨肾综合征出血热(HFRS)并发中枢神经系统损伤患者的心电图(ECG)改变与损伤原因、严重程度及预后的关系。方法前瞻性研究HFRS并发中枢神经系统损伤患者ECG的变化,统计并分析ECG在不同患者中的异常类型及异常发生率。结果HFRS并发中枢神经系统损伤患者ECG异常率与总的HFRS患者ECG异常率比较差异有显著性(P<0.01);与无神经系统并发症的重型、危重型HFRS患者ECG异常率及心肌酶学水平比较差异有显著性(P值均<0.05);不同严重程度、不同预后患者ECG异常率比较差异有显著性(P值分别为<0.05、<0.01);不同损伤原因患者ECG异常率比较差异无显著性(P>0.05);心电图逐渐改善患者预后良好。结论HFRS并发中枢神经系统损伤患者的ECG改变与中枢神经系统损伤有关,与损伤严重程度及预后密切相关。

Objective To explore the relationship between cardiogram in patients with hemor-rhagic fever with renal syndrome (HFRS) complicating damage of the central nervous system (CNS) andthe types of damages,the degrees of patients’condition and the prognosis.Methods A prospective sur-vey on changes of cardiogram in HFRS patients with CNS complications was conducted.The incidence andtypes of abnormal ECG were statistically analyzed in all patients.Results There are significant differencesabout the incidence of abnormal ECG and the myocardial enzyme between the HFRS patients with CNScomplications and all the patients with HFRS(P<0.01),and the patients, which were severe type or verysevere type without CNS complications (P<0.05).There are significant differences among different thedegrees of patients’condition or different prognosis (P<0.05,P<0.01 respectively).There aren’t sig-nificant differences among different causes of damages (P>0.05).The patients with ameliorating ECGhad a eusemia.Conclusions The changes of ECG of HFRS patients with CNS complications are relatedwith the degrees of CNS damages and the prognosis.