期刊文献+

己酮可可碱治疗炎性关节病的机制和前景展望 被引量:2

Mechanism of pentoxifylline used in inflammatory arthropathy
下载PDF
导出
摘要 炎性关节病是各种非化脓性炎症性关节炎的总称,常见的有类风湿关节炎(RA)、强直性脊柱炎(AS)、反应性关节炎、银屑病关节炎、炎性肠病性关节炎等,其中后几种疾病属于脊柱关节病(SpA)的范畴.炎性关节病患病率高,由于缺乏特异治疗,致畸致残率很高,严重影响了患者的生活质量,给社会和家庭带来了沉重的经济负担.
作者 张莉芸
机构地区 解放军总医院
出处 《临床药物治疗杂志》 2005年第4期31-36,共6页 Clinical Medication Journal
  • 相关文献

参考文献32

  • 1[1]Moller DR. Treatment of sarcoidosis --from a basic science point of view. J Intern Med,2003,253:31 ~40
  • 2[2]Anaya JM, Espinoza LR. Phosphodiesterase inhibitor pentoxifylline: an antiinflammatory/immunomodulatory drug potentially useful in some rheumatic diseases. J Rheumatol, 1995,22:595~ 599
  • 3[3]Strieter RM, Remick DG, Ward PA, et al. Cellular and molecular regulation of tumor necrosis factor - alpha production by pentoxifylline. Biochem Biophys Res Commun, 1988, 155:1230~ 1236
  • 4[4]Morgan TR, McClain CJ. Pentoxifylline and alcoholic hepatitis.Gastroenterology ,2000,119:1787 ~ 1791
  • 5[5]Benbernou N, Esnault S, Potron G, et al. Regulatory effects of pentoxifylline on T - helper cell - derived cytokine production in human blood cells. J Cardiovasc Pharmacol, 1995,25 (suppl.2) :S75 ~S79
  • 6[6]Moller DR, Wysocka M, Greenlee BM,et al. Inhibition of human interleukin- 12 production by pentoxifylline. Immunology,1997,91:197 ~203
  • 7[7]Rieckmann P, Weber F, Gunther A, et al. Pentoxifylline, a phosphodiesterase inhibitor, induces immune deviation in patients with multiple sclerosis. J Neuroimmunol, 1996,64:193 ~ 200
  • 8[8]Silva JC,Rocha MF, Lima AA, et al. Effects of pentoxifylline and nabumetone on the scrum levels of IL - 1 beta and TNFalpha in rats with adjuvant arthritis. Inflamm Res,2000,49:14 ~ 19
  • 9[9]Kiely PD, Gillespie KM, Oliveira DB. Oxpentifylline inhibits tumor necrosis factor - alpha mRNA transcription and protects against arthritis in mercuric chloride - treated brown Norway rats. Eur J Immunol, 1995,25:2899 ~ 2906
  • 10[10]Chen YL, Le - Vraux V, Giroud JP, et al. Anti - tumor necrosis factor properties of non - peptide drugs in acute - phase responses. Eur J Pharmacol, 1994,271:319 ~ 327

二级参考文献8

  • 1Huang F, Gu J, Zhao W, et al. One-year open-hbel trial of thalidomide in ankylosing spondylitis. Arthritis Rheum (Arthritis Care Res), 2002,47: 249-254.
  • 2Davis J, Huang F, Maksymowych WP. New therapies for ankylosing spondylitis: etanercept, thalidomide and pamidronate. Rheum Dis Clin North Am, 2003,29 : 501-517.
  • 3Huang F, Wei J, Breban M. Thalidomide in ankylosing spondylitis.Clin Exp Rheumatol, 2002,20: S158-161.
  • 4Huang F, Gu J, Zhao W, et al. Therapeutic effect and molecular targets of thalidomide in refractory ankylosing spondylitis. Arthritis Rheum,2001,44 : S275.
  • 5Gorman J, Sack K, Davis J. Treatment of ankylosing spondylitis by inhibition of tumor necrosis factor α. N Engl J Med, 2002,346:1349-1356.
  • 6Braun J, Brandt J, Listing J, et al. Treatment of active ankylosing spondylitis with infliximab: a randomized controlled multicentre trial. Lancet, 2002,359:1187.
  • 7Antoni C,Bmun J. Side effects of anti-TNF therapy: current knowledge. Clin Exp Rheumatol, 2002,20: S152-157.
  • 8黄烽,古洁若,赵伟,朱剑,张江林,余德恩.反应停治疗强直性脊柱炎的临床与实验研究[J].中华风湿病学杂志,2002,6(5):309-315. 被引量:75

共引文献43

同被引文献18

  • 1徐慧珍,李光中.己酮可可碱的药物特性和临床新用途[J].中国医院药学杂志,1997,17(4):178-179. 被引量:6
  • 2Stuart JM, Cremer MA, Townes AS, et al. Type Ⅱ collagen-induced arthritis in rats. Passive transfer with serum and evidence that IgG anticollagen antibodies can cause arthritis. J Exp Med, 1982, 155: 1-16.
  • 3Angelides NS. Continuous infusion treatment with pentoxifylline in patients with severe peripheral vascular occlusive disease. Angiology, 1986, 37: 555-564.
  • 4Bath PM, Bath-Hextall FJ. Pentoxifylline, propentofylline and pentifylline for acute ischaemic stroke. Cochrane Database Syst Rev, 2004, (3): CD000162.
  • 5Ustunsoy H, Sivrikoz MC, Tarakcioglu M, et al. The effects of pentoxifylline on the myocardial inflammation and ischemia- reperfusion injury during cardiopulmonary bypass. J Card Surg, 2006, 21: 57-61.
  • 6Haque K, Mohan P. Pentoxifylline for neonatal sepsis. Cochrane Database Syst Rev, 2003, (4): CD004205.
  • 7Wanchu A, Bhatnagar A, Bambery P, et al. Prevention of opportunistic infections in HIV infection by pentoxiphylline.Indian J Med Res, 2006, 124: 705-708.
  • 8Clerici M, Piconi S, Balotta C, et al. Pentoxifylline improves cell- mediated immunity and reduces human immunodeficiency virus (HIV) plasma viremia in asymptomatic HIV-seropositive persons. J Infect Dis, 1997, 175: 1210-1215.
  • 9Danielsson A, Karlsson E, Delle U, et al. The biological effect of pentoxifylline on the survival of human head and neck cancer cells treated with continuous low and high dose-rate irradiation. J Cancer Res Clin Oncol, 2005, 131: 459-467.
  • 10Goodfield MJ, Rowell NR. Treatment of peripheral gangrene due to systemic sclerosis with intravenous pentoxifylline. Clin Exp Dermatol, 1989, 14: 161-162.

引证文献2

二级引证文献3

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部