原发性肝癌术后复发的治疗(附58例报告)

Treatment of Recurrence Following Surgery for Primary Liver Cancer:A Report of 58 Cases

[目的]探讨原发性肝癌术后复发治疗的疗效。[方法]回顾性分析58例复发性肝癌以手术切除和非切除序贯综合治疗的效果,其中手术切除20例,38例不能切除者采取栓塞化疗和瘤内注射无水乙醇、微波固化、射频治疗、冷冻及抗癌中药等非切除的序贯综合治疗。[结果]从复发再治疗算起,再切除术后患者1、3、5年生存率分别为85.0%(17/20)、50.0%(9/18)、31.3%(5/16),非切除治疗组患者1、3、5年生存率分别为60.5%(23/38)、16.7%(6/36)、8.8%(3/34)。[结论]手术切除、序贯综合治疗复发性肝癌是有效的方法。

[Purpose]To investigate the treatment efficacy of recurrent hepatocarcinoma following surgery. [Methods] A retrospective analysis of 58 cases with recurrent hepatocarcinoma following hepatectomy or sequent comprehensive treatment. Among them, 20 cases were treated with hepatectomy, the other 38 nonresectable cases with various sequential combinations of therapy, such as chemoebolization, inter tumor injection of ethanol, microwave coagulation, cryosurgery, radio-frequency, radiotherapy, and anti-cancer Traditional Chinese Medicine. [Results] The rates of 1-, 3-, 5-year survival from rucurrence were 85.0% (17/20), 50.0% (9/18), and 31.3% (5/16) respectively in surgery group, 60.5% (23/38),16.7% (6/36), and 8.8% (3/34) respectively in nonresectable group. [Conclusion] Hepatectomy and sequential comprehensive therapy is effective modality for the recurrent hepatocarcinoma.