肺炎衣原体感染与冠心病相关性研究

Association between the chlamydia pneumonias infection and coronary hear disease

目的探讨肺炎衣原体感染与冠心病的相关性。方法采用酶标法测定冠心病组(120例)和对照组(120例)血清CP特异性抗体IgM。结果稳定冠心病组(72例)CPIgM阳性5例(6.94%),急性冠脉综合症组(23例)阳性2例(8.69%),冠心病合并心衰组(25例)阳性3例(12.0%),正常对照组(120例)阳性8例(6.66%)。稳定心绞痛组、急性冠脉综合症组、冠心病合并心衰与正常对照组相比,差异无显著性(P>0.05)。120例冠心病人不同年令组间、性别比较差异无显著性(P>0.05)。结论CPIgM感染与冠心病没有良好的相关性。

Objective To investigate the association between the chlamydia pneumonias (CP) infection and coronary heart disease (CHD).Methods Enzyme link immunosorbent assay (ELISA) methods were adapted of examine the specific antibody IgM of CP in plasma.120 CHD patients and 120 healthy volunteers were involved in the study.Results The positive rate for CPIgM was 6.94% ( 5 cases ) and 8.69%(2 cases) in stable angina pectoris(72cases) and acute coronary syndrome(23 cases); 12%(3 cases) and 6.66%(8 cases) in CHD with heart failure (25 cases) and normal controls(120 cases) respectively.There were no significant difference in groups of stable angina pectoris/acute coronary syndrome,CHD with heart failure and normal controls.The groups of stable angina pectoris,acute coronary syndrome,CHD with heart failure and normal controls.The groups of CHD with different age,sex showed no difference.Conclusion CPIgM infection had no significant association with CHD.