氯诺昔康复合异丙酚用于人工流产的临床观察

Analgesic Effect of Lornoxicam-Diprovan in Induced Abortion

目的:观察氯诺昔康复合异丙酚用于人工流产的临床效应。方法:早孕妇女100例,随机分为A(异丙酚2.5mg/kg)、B(氯诺昔康8mg+异丙酚2mg/kg)两组,每组50例。观察意识消失时间、苏醒时间、离院时间,同时记录有无头晕、呕吐等副作用及术中出血量,采用视觉模拟评分法(VAS评分)分别对术后30min、手术当天、术后第2天患者的疼痛情况进行评分并记录术后子宫出血量及副作用。结果:B组异丙酚的总用量较少、苏醒时间和离院时间更短(P<0.05),术后30min、手术当天、术后第2天患者的VAS评分更低(P<0.05),呼吸、循环功能抑制较轻(P<0.05);术中、术后出血量及不良反应两组间无差异(P>0.05)。结论:人流术中氯诺昔康复合异丙酚可降低异丙酚用量,减少呼吸、循环功能抑制,缩短苏醒时间及离院时间,不增加术中和术后子宫出血量,可明显减轻术后疼痛。

Objective:To observe the analgesic effect of lornoxicam-diprovan in in duced abortion.Methods:One hundred early pregnant women patients were randomly a llocated to two groups,A group(diprovan 2.5 mg/kg),B group(lornoxicam 8 mg+dipro van 2 mg/kg).The losing consciousness time,reviving time and leaving time were o bserved,and bleeding volume and side effects such as swirling and vomiting were also observed.Postoperative pain was assessed by VAS-score at 30 min,1 d,2 d aft er end of surgery,postoperative side-effects and postoperative bleeding volume w ere also assessed.Results:In lornoxicam-diprovan group,the dose of diprovan was less,reviving time and leaving time were shorter,VAS-scores at different time lo wer (P < 0.05),the inhibition of respiratory and circulation function was smalle r(P < 0.05).Conclusion:Lornoxicam-diprovan used in induced abortion could reduce the dose of diprovan,lessen the inhibiton of respiratory and circulation functi on,shorten reviving time and leaving time,not increase the bleeding volume,reduc e the postoperative pain.