血吸虫病直肠癌切除术后内部肛门括约肌的疲劳率指数变化(英文)

THE CHANGE OF FATIGUE RATE INDEX OF INTERNAL ANAR SPHINCTER IN SCHISTOSOMIASIS PATIENTS WITH POSTOPERATIVE RECTAL CARCINOMA

目的探讨血吸虫病直肠癌切除术后内部肛门括约肌的疲劳率指数变化。方法术前,对75例血吸虫病直肠癌术后患者的临床资料进行回顾性评估,其中包括肛门部的静压和挤压的测定,以及疲劳率和疲劳率指数的研究,术后6月,经重复测压及疲劳率和疲劳率指数评估直肠的自制力。疲劳率为每分钟测得的直肠压力变化,疲劳率指数=(挤压-静压,mmHg)/[-(疲劳率,mmHg/min)]。结果术前平均静压和挤压为55mmHg和127.5mmHg,术后平均静压和挤压为30mmHg和74.5mmHg,术前平均疲劳率指数为3.0min,术后1.3min,术前术后疲劳率指数有显著差异(P<0.05)。结论直肠自制力受内部肛门括约肌的疲劳率指数影响,直肠癌术后疲劳率指数的变化展示其内部肛门括约肌机能的损伤程度,疲劳率指数下降越大,其内部肛门括约肌的损伤越重。

Objective To study the change of fatigue rate index (FRI) of internal anal sphinecter in schistosomiasis patients with postoperative rectal carcinoma. Methods 75 schistosomiasis patients with postoperative rectal carcinoma were evaluated via patients' clinical data, including anal resting pressure and squeeze pressure, the fatigue rate(FR)and FRI assay. Six months postoperation, repeated manometric studies, the FR and FRI were performed to assess the level of continence. The FR was the measurement of the change in pressure per minute. The FRI=(squeeze pressure-resting pressure, mmHg)/\[-(fatigue rate, mmHg/minute)\]. Results Before operatien, mean resting and squeeze pressures were 55 mmHg and 127.5 mmHg, and postoperation, mean resting and squeeze pressure were 30 mmHg and 74.5 mmHg. Mean FRI was 3.0 minutes for preoperative patients, 1.3 miutes for postoperative patients. Compared with preoperative and postoperative data in patients, the FRI change was significant (P<0.05). Conclusion Contienence of rectum is influenced by FRI of function of the internal anal sphincter, the change of FRI after resecting rectal carcinoma showed the damage degree of internal anal sphincter function, and the more the decrease of FRI, the more the damage to the internal anal sphincter.