摘要
目的:通过研究不同负荷有氧运动对大鼠动脉粥样硬化发生发展过程中血浆及心肌AngII含量的影响,为动脉粥样硬化运动处方的制定提供一定的理论参考。方法:雄性Wistar大鼠40只,随机分为正常对照组(NC);动脉粥样硬化组(AS);动脉粥样硬化+60min有氧运动组(ASAT1);动脉粥样硬化+120min有氧运动组(ASAT2)。放免法测定血浆及心肌组织AngII。结果:AS组与NC组相比,血浆AngII显著升高(P<0.05);心肌AngII显著升高(P<0.05)。ASAT1、ASAT2两组与AS组相比,血浆AngII显著下降(P<0.05);ASAT1组心肌AngII显著低于AS组(P<0.05)。ASAT2与ASAT1相比心肌AngII显著升高。结论:60min有氧训练可以使大鼠动脉粥样硬化发生发展过程中血浆和心肌组织AngII降低,延缓动脉粥样硬化的进程;120min有氧训练与60min有氧训练相比,使该过程中大鼠血浆和心肌AngII升高。从一定程度上说明较长时间的有氧运动并不能进一步改善动脉粥样硬化。
This paper studied the effect of aerobic exercise at different workload on AngII in plasma and myocardium in the process of atherosclerosis evolution in order to provide theoretical basis to setup exercise prescription for atherosclerosis.40 male Wistar rats were divided into four groups randomly,normal control group (NC),atherosclerosis group (AS),atherosclerosis and aerobic exercise for 60 minutes everyday (ASAT1),atherosclerosis and aerobic exercise for 120 minutes everyday (ASAT2).The result showed that comparing with NC group,AngII in plasma and myocardium in AS group was significantly increased.Comparing with AS group,AngII in plasma in ASAT1 and ASAT2 group was significantly decreased.It concludes that 60 minutes aerobic exercise can delay the process of atherosclerosis by decreasing AngII in plasma and myocardium.Comparing with 60 minutes aerobic exercise,120 minutes aerobic exercise increase AngII in plasma and myocardium.Aerobic exercise for longer time cannot do better for atherosclerosis than shorter time of aerobic exercise do.
出处
《体育科学》
CSSCI
北大核心
2005年第7期31-34,共4页
China Sport Science
