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慢性酒精性肝病大鼠肝脏白细胞介素10的表达及茶多酚的影响 被引量:8

Expression of IL-10 in the livers of rats with chronic alcoholic liver diseases
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摘要 茶多酚(TP)是从天然植物茶叶中分离提纯的多酚类化合物复合体,具有护肝、抗氧化和免疫调节等多方面的作用[1].拟通过观察茶多酚对酒精性肝损伤动物模型的保护作用及白细胞介素-10(IL-10)在动物肝脏中的表达,探讨IL-10在酒精性肝病发病中的作用以及茶多酚防治酒精性肝病的机制.
出处 《中华肝脏病杂志》 CAS CSCD 北大核心 2005年第7期551-552,共2页 Chinese Journal of Hepatology
关键词 慢性酒精性肝病 大鼠 肝脏 白细胞介素10 基因表达 茶多酚 TP 肝组织 免疫组织化学 Liver diseases, alcoholic Interleukin-10 Immunohistochemistry Tea polyphenol
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  • 1Karamanlioglu B, Yuksel M, Temiz E, et al. Hepatobiliary scintigraphy for evaluating the hepatotoxic effect of halothane and the protective effect of catechin in comparison with histo-chemical analysis of liver tissue. Nuc Med Commun, 2002, 23: 53-59.
  • 2Lichtman SN, Lemasters JJ. Role of cytokines and cytokine-producing cells in reperfusion injury to the liver. Semin Liver Dis, 1999,19: 171-187.
  • 3Sermon F, Le Moine O, Gustot T, et al. Chronic alcohol exposure sensitizes mice to galactosamine-induced liver injury through enhanced keratinocyte chemoattractant and defective IL-10production. J Hepatol, 2003, 39: 68-76.
  • 4Gonzalez-Quintela A, Vidal C, Lojo S, et al. Serum cytokines and increased total serum IgE in alcoholics. Ann Allergy Asthma Immunol, 1999, 83: 61-67.
  • 5Hill DB, D'Souza NB, Lee EY, et al. A role for interleukin-10 in alcohol-induced liver sensitization to bacterial lipopolysaccharide.Alcohol Clin Exp Res, 2002, 26: 74-82.
  • 6Grove J, Daly AK, Bassendine MF, et al. Interleukin 10 promoter region polymorphisms and susceptibility to advanced alcoholic liver disease. Gut, 2000, 46: 540-545.
  • 7Okabe S, Ochiai Y, Aida M, et al. Mechanistic aspects of green tea as a cancer preventive: effect of components on human stomach cancer cell lines. Jpn J Cancer Res, 1999, 90: 733-739.
  • 8Ooshima T, Minami T, Matsumoto M, et al. Comparison of the cariostatic effects between regimens to administer oolong tea polyphenols in SPF rats. Caries Res, 1998, 32: 75-80.

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