摘要
目的探讨1-溴-2,4-二氟苯合成工艺的经济方法。方法以间苯二胺为原料,经Schiemann反应及溴化,合成1-溴-2,4-二氟苯。结果总收率为40%,纯度大于98%。结论本法具有产率高,成本低的优点。
Objective To explore an economical method to synthesize the 1-bromo-2,4-difluorobenzene.Methods The compound was synthesized from m-phenylene diamine by Schiemann reaction and bromination.Results The total yield reached 40% and purity was over 98%.Conclusion This method has feature of high yield and low cost.
出处
《咸宁学院学报（医学版）》
2005年第3期169-170,共2页
Journal of Xianning Univarsity(medical Sciences)
关键词
1-溴-2
4-二氟苯
间苯二胺
间二氟苯
合成
1-bromo-2,4-difluorobenzene
M-phenylenediamine
M-difluorobenzene
Synthesis
