高剂量率腔内后装放射与外照射治疗原发性支气管肺癌（附31例报告）

PRIMARY BRONCHOGENIC CARCINOMA TREATED WITH HIGHDOSE RATE OF ENDOBRONCHIAL BRACHYIRRADIATION AND EXTERNAL IRRADIATION(A REPORT OF 31 CASES)

应用高剂量率腔内后装放射加外照射治疗原发性支气管肺癌３１例。腔内后装放射剂量为６００～８００ｃＧｙ／次，参考距离１０～１５ｍｍ，总剂量为１８００～３０００ｃＧｙ。外照射剂量为５０００～６００ＯｃＧｙ。治疗后临床症状缓解，肿块消失与支气管通畅者１０例（占３２．２％）；症状缓解、肿块缩小５０％以上者１６例（占５１．８％）。总有效率为８８．１％。治疗期，有１例病人出现咯血，３例出现支气管痉挛，１例治疗后出现高热和白细胞增高，但多数病人均能耐受。

Thirty-one cases of primary bronchogenic carcinoma were treated by high-dose rate of endobronchial brachyirradiation (ENBI)and external beam irradiation (EBI). The results showed that the high-dose of ENBI was 60O-800 cGy for each dose of one patient, its referred distance was 10-15 mm and the total dosage was 1800-3000 cGy, added with 5000-6000 cGy of EBI. After the completion of treatment,10 patients (32. 2%) had remission of clinical symptoms with good bronchial ventilation and the local tumors of all patients disappeared, 16 patients (51. 8%) had remission of clinical symptoms with disappearance of more than 50% of tumor mass. The total effective rate was 88. 1%. During therapeutic stage there were sideeffects occurred: bronchial spasm 3 patients, homoptysis 1, high fever and leucocytosis 1.