激素和肝素对延时再植断肢肌肉微血管超微结构的研究

AESTRACTS THE STUDY OF COMBINED DXM AND HAPARIN ON ULTRAMICROSTRUCTURE OF MDSCLE AND MICROCIRCULATION DURING DELATED REPLANTATION OF LIMB

用２０只ＳＤ大白鼠，右侧后肢制作断肢模型。在股血管显微修复血流再通前，Ａ组用大剂量激素和肝素联合股动脉内灌注和全身用药；Ｂ组仅用肝素；Ｃ、Ｄ组对照。术后３小时和７２小时取比目鱼肌行透射电镜观察。结果显示用大剂量激素和肝素，有利于减少延时再植时组织的缺血再灌注损伤。

rough the ultramicroscopic observation on muscle and microcirculation, Group A,where a largeamount of DXM combined with heporin was given svstematically and locally into the femoral artery of the severed limb before replantation, and in Group B only heporin was given, and Group C and D ascontrol.The results showed that if the hormone and heparin were administred in large dosage, it wasadvantageous to reduce the tissues from reperfusion injury during delayed replantation.