全威凯洛欣与β-七叶皂苷钠治疗周围神经损伤的研究

Quan Wei Kai luoxin and Sodium β-Aescin on the Treatment of Prepheral Nerve Injury

目的:探讨全威凯洛欣(神经节苷脂,gangliaoside)与β-七叶皂苷钠对周围神经损伤的临床疗效。方法:自1998年1月至2003年1月对止血带引起下肢神经损伤患者18例,损伤后12例应用全威凯洛欣与β-七叶皂苷钠,6例应用维生素B1、维生素B12。伤后1d、7d、15d、30d,患肢行电生理检查,评价神经功能恢复情况。结果:用全威凯洛欣与β-七叶皂苷钠组神经功能恢复明显,差异有显著性P<0.05。结论:全威凯洛欣与β-七叶皂苷钠促进周围神经损伤后神经再生及功能恢复。

Objective To explore the therapeutic efficiency of Quan wei Kai luo xin,(QWKL,gangliaoside) and sodium β-Aescin (SA) in treating patients with injured prepheral nerve.Methods From January 1998 to January 2003,after tourniquet lower limb nerve injury patients 18 case.The 12 case were treated with QWKL and SA.6 case were treated with VitB_1 and VitB_(12). After treatment,the 1、7、15 and 30 days tibianerve was measured by electrophysiology.Results In the treatment group, nerves function recovery was obviously.Conclusion The QWKL and SA are capable of promoting the functional recovery after peripheral never injury.