摘要
目的观察健脾理气活血方对脾虚气滞型功能性消化不良(FD)的疗效。方法将80例FD患者随机分为两组,治疗组(50例)服用健脾理气活血方,对照组(30例)服用枳术丸,疗程4周。观察两组治疗前后中医症状总疗效及单项症状疗效,治疗组治疗前后胃动素、胃泌素及钡条胃排空情况。结果治疗组总体疗效明显优于对照组。治疗组在腹胀、腹痛、早饱、乏力、纳差5个症状的改善方面明显优于对照组(均P<0.05),而恶心、嗳气的改善两组间无明显差异(P>0.05)。治疗后胃动素较治疗前升高,有极显著差异(P<0.01),胃泌素较治疗前明显升高(P<0.05)。治疗组有胃排空延迟者占42%,治疗后85.7%的胃排空延迟者胃排空恢复正常。结论健脾理气活血方对脾虚气滞型功能性消化不良有明显疗效。
Objective To observe the effect of the prescription of invigorating spleen with regulating qi and promoting blood circulation (PIGP) in treating functional dyspepsia (FD) of the spleen-deficiency and qi-stagnation symptoms. Methods 80 patients were divided into two groups randomly : treatment group (50 cases) treated by the prescription of PIGP, and ontrol group (30 cases) treated by Zhizhu pills. The treatment period is 4 weeks. The clinical symptoms of two groups, gastrin, motilin and barinm gastric emptying results of the treatment group are evaluated before and after the treatment. Results The overall effective rate of the treatment group was superior to the control group significantly. The single effective rate of the treatment group on epigastric fullness, abdominal pain, early satiety, inertia and anorexia were superior to the control group (P <0.05). There were no significant differences on belch and nausea between two groups. In the treatment group, the gastrin and motilin were significantly increased than that of before treatment. In the treatment group, there were 42% patients with delayed gastric emptying. After the treatment, 85.7% patients got normal gastric emptying in these cases. Conclusion The prescription of PIGP is effective in treating FD of the spleen-deficiency and qi-stagnation symptoms.
出处
《中国中医药信息杂志》
CAS
CSCD
2005年第7期11-13,共3页
Chinese Journal of Information on Traditional Chinese Medicine
关键词
功能性消化不良
脾虚气滞型
健脾理气活血方
functional dyspepsia
syndrome of spleen-deficiency and qi-stagnation
prescription of PIGP