脑出血早期应用七叶皂苷钠治疗的临床观察

The Sodium Aescinate for the Early Intracerebral Hemorrhage.

目的观察脑出血早期应用七叶皂苷钠治疗的临床疗效。方法采用前瞻性随机对照方法分为治疗组和对照组,治疗组在对照组治疗的基础上应用七叶皂苷钠20mg加生理盐水250mL静脉输注,每天1次,连用21d。结果治疗组和对照组总有效率分别为83.82%和57.58%(P<0.01)。结论七叶皂苷纳有良好的改善微循环作用,对血肿周边缺血区有着重要意义,对脑出血急性期有明显疗效。

Objective To study the clinical efficiency of Sodium Aescinate in the patients with early acute intracerebral hemorrhage.Methods All patients with early acute intracerebral hemorrhage were divided into treatment group (68 pts) and control groups (66 pts).The pts in treatment group, on the treatment basis of control group, were treated by sodium aescinate (20 mg of Sodium Aescinate added in 250 mL normal saline for intravenous infusion,once a day) for 21 day.Results The efficiency of treatment group and control group were 83.82% and 57.58%,respectively (P<0.01).Conclusion The results suggest that sodium aescinate promote microcirculation in perihematomal ischemia region for patients with early acute intracerebral hemorrhage.