摘要
本文用ELISA方法检测了30份母初乳中脊髓灰质炎病毒Ⅰ、Ⅱ、Ⅲ型、麻疹病毒及风疹病毒IgA抗体。结果显示,母乳中IgA抗体水平≥1:20的,脊髓灰质炎病毒Ⅰ、Ⅱ型均占86.7%,Ⅲ型占83.3%,麻疹病毒占66.7%,风疹病毒占60%。母乳中这些特异性抗体的存在,一方面反映了母亲粘膜所接触的抗原,可为病原体的流行病学研究提供依据;另一方面说明母乳喂养对保护婴儿免于感染有着重要意义。
Concentration of IgA antibodies against poliovirus type Ⅰ、Ⅱ、Ⅲ, measles virus and rubella virus in 30 samples of colostrum were determinded by enzymelinked im-munosorbent assay. The results showed positive rates of the IgA antibodies (literes≥1 : 20) were86. 7% in poliovirus Ⅰ、Ⅱ,83. 3% in poliovius Ⅲ ; 66. 7% in measles virus and 60% in rubella virus. The specific antibodied in maternal milk reflect antigenic exposure on mucosal membranes of these mothers and might beused to study epidemiology of pathogens, and it might play an important role in breast-fed infants preventing various infections.