早产儿胃肠喂养的临床研究

目的探讨早产低体重儿胃肠喂养的体重增长及喂养并发症.方法将出生24h内入院、住院时间≥10天、无喂养禁忌症的早产儿按体重≤2000g或＞2000g分为A组和B组,分别予早产儿配方奶及标准Ⅰ期婴儿配方奶以最大限度的胃肠喂养,比较两组的早期体重下降、平均体重增长和胃肠耐受性.结果两组早期体重下降数(85.7%vs 80.9%)、最大体重下降值(7±4.8%vs 5.5±3.9%)、体重下降＞10%者(17.9%vs 6.4%)均无统计学差异(P均＞0.05);两组晚发性酸中毒发生率(14.3%vs 6.4%)及1～4w胃肠不耐受发生率亦无统计学差异(P均＞0.05);A组第2w后、B组第3w后的平均体重增长均＞10g/(kg.d).结论选择合适的奶方和喂养措施,可以使早产低体重儿达到较好的体重增长.

Objective:To investigate the weight growth and complication of gastroenteric feed of premature in gastroenteric feed. Methods: Divided premature of which birth in 24 hours、hospitalization days over 10 days,no contra-indication of gastroenteric feed, into group A and group B acording to birth-weight under or over 2000g; fed them separately with premature formula milk and common infant formula milk(I) to the greatest possible advantage.Compared the early weight-lost,mean value of weight-increase and gastroenteric tolerance of group A and group B . Results:There were no significant difference between group A and group B on the number of early weight-lost(85.7% vs 80.9%),the level of most weight-lost(7±4.8% vs 5.5±3.9%) and the rate of weight-lost over 10 percent(17.9% vs 6.4%)(P>0.05);also on the frequency of late matebolic acidosis(14.3% vs 6.4%) and the untolerance of gastroenter in 4 weeks of hospitalization(P>0.05). The mean value of weight-increase was over 10g/kg/d , from 2 weeks later in group A and 3 weeks later in group B. There were no NEC happened bonth in A and group B. Conclusion:Premature can growth well in weight on providing suitable milk and proper method of feeding.