幽门螺杆菌感染与再发脑梗死的关系研究

Correlation between Helicobacter pylori infection and relapsed cerebral infarction.

目的探讨幽门螺杆菌(HP)感染与再发脑梗死的关系。方法采用病例对照的研究方式,选择再发脑梗死患者85例(A组)、初发脑梗死患者85例(B组)和健康体检者85例(C组)。检测3组血清HP特异性抗体IgG(HP-IgG)。结果A、B、C3组的HP-IgG阳性率分别为92%(78/85)、72%(61/85)和54%(46/85),A组与B组比较差别有统计学意义(χ2=11.40,P<0.01);A组与C组比较差别有统计学意义(χ2=30.52,P<0.01);B组与C组比较差别有统计学意义(χ2=5.67,P<0.05)。结论再发脑梗死患者的HP感染率高于初发脑梗死患者,但二者的HP感染率明显高于未发生脑梗死者。

Objective To study the association between Helicobacter pylori (HP) infection and relapsed cerebral infarction.Methods By the case-control study,85 cases of relapsed cerebral infarction (group A),85 cases of initial cerebral infarction (group B) and 85 healthy controls (group C) were selected.HP specific antibody IgG (HP-IgG) was detected in the three groups.Results The positive rates of HP-IgG in the three groups were 92%(78/85),72%(61/85) and 54%(46/85),respectively,and there was statistically different between group A and group B (χ 2=11.40,P<0.01),between group A and group C (χ 2=30.52,P<0.01)) and between group B and group C (χ 2=5.67,P<0.05).Conclusion The infection rate is higher in relapsed cerebral infarction group than in initial cerebralinfarcti on group and the infection rate in both relapsed cerebral infarction group and initial cerebralinfarcti on group is higher than in healthy subjects.