磷酸钙骨水泥注射椎体成形术的生物力学研究

The biomechanical influence of vertebroplasty with filling with Autosolidification Calcium Phosphate Cement.

目的探讨磷酸钙骨水泥注射椎体成形术后对椎体的力学影响。方法建立前屈方向加载单椎体骨折模型,对新鲜尸体胸腰椎椎体标本行磷酸钙骨水泥(CPC)成形强化,骨折前、成形后分别行屈曲压缩力学实验。结果椎体内注射CPC能明显恢复骨折椎体的力学性质。但其恢复的程度与注入量有关,其强度最高可恢复到原来正常情况下的2倍,而刚度可超过原来的14.70%左右。椎体的强度和刚度分别增加52.38%(P<0.05)和14.70%(P<0.05)。结论椎体内注射CPC能明显恢复骨折椎体的力学性质。

Objective To investigate the biomechanical influence of vertebroplasty using Calcium Phosphate Cement (CPC) on vertebral body. Methods Six fresh cadaver specimens were applied to make spine unit. All were underwent flexion - axial loading to result in vertebral body fracture. Following reduction ,the middle fractured vertebral body were strengthened by the method of vertetroplasty , using Calcium Phosphate Cement (CPC) . Before fracture and after vertebroplasty , all were conducted biomechanical test . Results After being injected CPC into bone trabecular interspaces,the fractured vertebral bodies can markly restore its strength and stiffness, which had 2 times of its initial strength and14.70% of its initial stiffness at topmost. The degree of restoration was related to the CPC injecting volume. After being packed CPC to the space in the fractured vertebral body, the fractured body increased its strength and stiffiness by 52.38% (P<0.05) and 14.70 %(P<0.05) separately in comparison with its initial situation. Conclusion After being injected CPC into bone trabecular interspaces, the fractured vertebral bodies can markly restore its strength and stiffness. [