脑梗死与颈动脉粥样硬化斑块的关系

Association of carotid atherosclerosis plaque with cerebral infarction

目的探讨脑梗死与颈动脉粥样硬化斑块的关系。方法对64例脑梗死患者和30例对照组进行颈动脉彩色多普勒超声检查。结果病例组斑块检出率79.7%,显著高于对照组斑块检出率16.7%(P<0.001)。颈动脉分叉处硬化斑块检出率约为55.4%,显著高于颈总动脉和颈内动脉斑块检出率(24.3%,20.3%)(P<0.001)。病例组中、重型患者软斑块检出率(28/45)显著高于轻型患者斑块检出率(3/19)(P<0.001)。结论脑梗死发病与颈动脉粥样硬化斑块相关。软斑块与脑梗死病情的轻重有一定关系。脑梗死患者颈动脉彩色多普勒超声检查有重要临床意义。

Objective To investigate the relationship between carotid atherosclerosis plaque and cerebral infarction. Methods The carotid arteries of 64 cases suffered cerebral infarctions were examined by ultrasound and compared with 30 controls. Results Carotid plaques were found in 51 cases of 64 patients and the prevalence was 79.7%. Five cases with carotid plaques were checked out in the control group and the prevalence was 16.7%. There was significant difference between the tow groups (P<0.001). The plaque prevalence in bifurcation was 55% and that was higher than those in common carotid artery and internal carotid artery(P<0.001)The soft plaques were found more common in moderate and server cases than that in mild cases(P<0.001). Conclusion There was correlation between carotid atherosclerosis plaque and the onset of cerebral infarction. The severity of infarction was dependent partly on the character of plaque. Ultrasonod examination may be useful for evaluating carotid atherosclerosis plaque in patient with cerebral stroke.