胸腔细管引流同时口服强的松治疗结核性大量胸腔积液的疗效分析

Analysis of Curative Effect Combination Therapy of Glucocorticoid with Drainage-microtube for Serious Typical Tuberculous Symptom in Associatin with Tuberculous Pleural Effusion

目的:探讨胸腔细管持续引流同时口服强的松治疗结核性大量胸腔积液并临床结核中毒症状较重患者的疗效。方法:对住院确诊的46例单纯性结核性大量胸腔积液并临床结核中毒症状较重患者随机分为治疗组和对照组。治疗组在规则抗结核基础上行胸腔细管持续引流并同时口服强的松,直至胸液消失后拔管;对照组在规则抗结核基础上予常规胸穿抽液,直至胸液消失。观察临床结核中毒症状、胸液压迫症状及胸液消失时间;胸膜粘连及肥厚、包裹性胸腔积液的发生率。结果:与对照组比较,治疗组临床结核中毒症状、胸液压迫症状及胸液的消失时间均显著缩短;胸膜粘连及肥厚、包裹性胸腔积液的发生率明显较低。结论:胸腔细管持续引流同时口服强的松是治疗结核性大量胸腔积液并临床结核中毒症状较重患者的有效治疗方法,具有良好的安全性及较强的可行性,疗效确切,值得临床推广应用。

Objective: To evaluate effect of combination therapy of glucocorticoid with drainage-microtube for treating patients with serious typical tuberculous symptom in association with tuberculous pleural effusion.Methods:46 patients with serious typical tuberculous symptom in association with tuberculous pleural effusion were randomly divided into treatment group and control group.The patients of treatment group were treated by glucocorticoid drainage-microtube.Aspiration for pleural effusion in the control group.Regular antituberculosis treatment was conducted for all patients.Results:The disappearance times of tuberculotic toxic symptoms and pleural effusion in the treatment group were signifcantly shorter than that in control group.The occurance rates of pleural thickning,pleural adhesion and pleural effusion in treatment group was less than that in control group.Conclusion:Glucocortocoid plus drainage-microtube therapy is a safe,convenient,and effective method for serious typical tuberculous symptoms in association with tuberculous pleural effusion.