黄芩正气胶囊的质量标准研究

Study on Quality Standard for Huangqin Zhengqi Capsule

目的建立黄芩正气胶囊的质量标准。方法采用TLC、HPLC法对黄芩正气胶囊进行定性鉴别;采用HPLC法测定其有效成分的含量。结果TLC可鉴别出与厚朴、广藿香相对应的斑点;HPLC法可鉴别苍术特征峰,并测定出橙皮苷、黄芩苷、和厚朴酚、厚朴酚的含量。结论所建立的质量标准简便可行、重复性好,可用于黄芩正气胶囊的质量监控。

Objective To establish a quality standard for Huangqin Zhengqi Capsules (HZC). Methods HZC was identified by TLC and HPLC and the effective components of HZC were determined by HPLC. Results The relevant spots in Cortex Magnoliae Officinalis and Herba Pogostemonis were identified by TLC, and the characteristic compounds of Rhizoma Atractylodis were identified by HPLC; the contents of hesperidin, baicalin, honokiol and magnolol could be determined by HPLC. Conclusion The quality standard is simple, feasible and repeatable, and can be used for quality supervisory and control in Huangqin Zhengqi Capsule.