期刊文献+

Draize眼刺激性试验的评价 被引量:18

下载PDF
导出
摘要 在药物安全性评价中,眼用药物及可能接触到眼的化学物质均应考虑进行眼刺激性试验,Draize试验是评价眼刺性的主要方法。作者综述了国外有关Draize眼刺激性试验的文献,并对其存在问题进行了讨探,提出改进的建议,希望有助于研究人员和评价人员对该试验的理解、运用和评价。
作者 王庆利 彭健
出处 《中药新药与临床药理》 CAS CSCD 2005年第4期301-304,共4页 Traditional Chinese Drug Research and Clinical Pharmacology
  • 相关文献

参考文献16

  • 1王红梅,马玲.眼刺激试验替代方法的研究进展[J].卫生毒理学杂志,2004,18(1):51-53. 被引量:2
  • 2Draize JH, Woodward G, Calvery HO. Methods for the study of irritation and toxicity of substances applied topically to the skin and mucous membrances [J]. J Pharmacol Expe Ther, 1944, 82:377 - 390.
  • 3Friedenwald .JS, Hughes WF, Hermann H. Acid - base tolerance of the cornea [J]. Arch Ophthlmol, 1944, 31:279 - 283.
  • 4Marzulli FN, Simon ME. Eye irritation from topically applied drugs and cosmetics: preclinical studies [J]. Am J Optom Arch Am Acad Optom,1971, 48:61-79.
  • 5Mishima S. Clinical pharmacokinetics of the eye [J]. Invest Ophthalmol Vis Sci, 1981, 21: 504.
  • 6Freeberg FE, Griffith JF, Bruce RD, et al. Correlation of animaltest methods with human experience for husehold products [J ]. J Toxicol Cutan Ocul Toxicol, 1984, 1: 53.
  • 7Griffith JF, Nixon GA, Bruce RD, et al. Dose- response studies with chemical irritants in the albino rabbit eye as a basis for selecting optimum testing conditions for predicting hazard to the human eye[J]. Toxicol Appl Pharmacol, 1980, 55:501 -513.
  • 8NAS committee for revision of NAS Publication. Dermal and eye toxicity tests. In: Principles and Procedures for Evaluating the Toxicity of Household Substances[M]. National Academy of Sciences, Washington, D. C,1977, 41-54.
  • 9Mishima S, Hedbys BO. Measurement of corneal thickness with the Haag - Streit pachometer[J]. Arch Ophthalmol, 1968, 80:710 - 713.
  • 10Buehler EV, Newmann A Comparison of eye irritation in monkeys and rabbits[J]. Toxicol Appl Pharmacol, 1964, 84:701-710.

二级参考文献44

  • 1Chiba K, Mskino 1, Ohuchi J, et al. Interlaboratory validation of the in vitro eye irritation tests for cosmetic ingredients (9) evaluation of cytotoxicity tests on HELA ceils. Toxicol in vitro,1999,13 : 199-208.
  • 2Okumura H, Arashima M, Ohuchi J, et al. Interlaboratory validation of the in vitro eye irritation tests for cosmetic ingredients(10) evaluation of cytotoxicity tests on CHL cells. Toxicol in vitro, 1999,13 : 199-208.
  • 3Okamoto Y, Ohkoshi K, ltageaki H, et al. Interlaboratory validation of the in vitro eye irritation tests for cosmetic ingredients (3) evaluation of the haomolysis test. Toxicol in vitro. 1999,13:115-124.
  • 4Pape WJW, Pfannenbecker V, Argembeaux H, et al. COLIPA validation project on in vitro eye irritation tests for cosmetic ingredients and finished products( phase 1 ) : the red blood cell test for the estimation of acute eye irritation potentials present status. Toxicol in vitro, 1999,13 : 343-354.
  • 5Gordon VC, Bergman HC. EYTEX^TM : an in vitro method for evaluation of ocular irritancy In vitro toxicology: approaches to valuation. Edited by Goldberg A. M, Marry Ann Liebert, New York, 1987. 293-302.
  • 6Matsukawa K, Masuda K, Kakishima H, et al. Interlaboratory validation of the in vitro eye irritation tests for cosmetic ingredients( 1 ) EYTEX^TM . Toxicol in vitro, 1999,13:209-217.
  • 7Courtellemont P, Pannetier M, Biesse JP, et al. Evaluation ofthe EYTEX^TM system in the COLIPA eye irritation program.Toxicol in vitro, 1999,13:295-304.
  • 8Bell E, Parenteau N, Gay R, et al. The living skin equivalent:its manufacture its organotypic properties and its responses to irritation. Toxicol in vitro, 1991,5 : 591-596.
  • 9Ohuchi J, Kasai Y, Sakamoto K, et al. Interlaboratory validation of the in vitro eye irritation tests for cosmetic ingredients (6) evaluation of MATREXTM . Toxicol in vitro, 1999, 13: 153-162.
  • 10Kurishita A, Katoh T, Ohsawa H, et al. Interlaboratory validation of the in vitro eye irritation tests for cosmetic ingredients (5) Skin^27M ZKll00 and tissue equivalent assay. Toxicol in vitro, 1999,13 : 139-151.

共引文献1

同被引文献150

引证文献18

二级引证文献43

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部