期刊文献+

佛山地区13324例居民血尿酸水平及相关指标分析 被引量:83

The Analysis of Blood Uric Acid Level and the Indications Associate with Hyperuricemia in 13 324 Foshan's Inhabitants
下载PDF
导出
摘要 目的了解佛山地区居民血尿酸水平和高尿酸血症与相关疾病的发生情况。方法对13324例健康体检者的血尿酸水平及血肌酐、尿素氮、胆固醇、甘油三酯、血糖和血压的测定结果进行统计分析。结果男性平均血尿酸水平为(349.8±97.6)μmol/L,女性为(276.2±84.3)μmol/L,男性的高尿酸血症发病率为22.6%,女性为11.6%,男性均显著高于女性(P<0.05,P<0.001)。高尿酸血症的发病率随年龄的增长而升高,不同年龄组之间有统计学差异(P<0.05)。高尿酸血症组的肾损害、高脂血症、高血糖、高血压的发生率显著高于尿酸正常组(P<0.05~0.01)。结论佛山地区高尿酸血症的发病率高于内地其他地区的调查结果,高尿酸血症的发生率随年龄的增长而升高,高尿酸血症患者更容易伴发肾损害、高脂血症、高血糖和高血压,应该引起人们的重视。 Objective:To investigate the blood uric acid level of Foshan's inhabitants, and to explore the correlation between hyperuricemia and boold biochemical examination,hypertention.Methods:All the clinical data of 13324 Foshan's health physical examination inhabitants were analysed. The health physical examination include to detect blood uric acid(BUA),blood urea nitrogen(BUN),serum creatinine(Scr), cholesterol(TC), triglycerides(TG), blood glucose (BG) and blood pressure(BP).Results:The mean of SUA was (349.8±97.6)μmol/L in male and (276.2±84.3)μmol/L in female(P<0.05). The prevalence of hyperuricemia was 22.6% in male and 11.6% in female. The blood uric acid level and the prevalence of hyperuricemia in the mail was significantly higher than in the female(P<0.05 and P<0.001)).The prevalence of hyperuricemia among different age groups was significantly variation(P<0.05).The prevalence of BUN, Scr, TC,TG,BS and BP increase was significantly higher in hyperuricemia group than in normal group(P<0.05~0.01). Conclusion:The prevalence of hyperuricemia in Foshan was Higher than other districts in China except Taiwan. The prevalence of hyperuricemia was more high by age.There were high prevalence of renal function descent, hyperlipaemia, high blood glucose and hypertension in hyperuricemia group. They should be paid more attention by people extensively.
出处 《中国中西医结合肾病杂志》 2005年第7期401-403,共3页 Chinese Journal of Integrated Traditional and Western Nephrology
基金 佛山市卫生局立项项目(No.2004165)
  • 相关文献

参考文献13

二级参考文献31

  • 1杨岫岩,唐福林.21家医院痛风住院构成比15年变化趋势分析[J].中华流行病学杂志,1996,17(1):10-12. 被引量:67
  • 2方圻 游凯 等.中国正常人血尿酸调查及其与血脂的关系[J].中华内科杂志,1983,22(7):434-434.
  • 3董德长 李占春 等.高尿酸血症性肾病[J].中华内科杂志,1986,25(9):543-543.
  • 4[9]Philips FS, Thiersh JB, Bendich A. Adenin intoxincation in vivo formation and deposition of 2,8 - dioxyademine in renal tubules. Pharmacal Exp Ther, 1952,104: 20 - 30.
  • 5[10]Tamg D- C, Lin H - Y, Shyong M - L, et al. Renal function in gout patients. Am J nephrol, 1995,15 : 31 - 37.
  • 6[11]Linnane JW, Burry AF, Emmchom BT. Urate deposists in the renal medulla: prevalent and nephrosclerosis. Am J Kidney Dis, 1995,25: 207 - 221.
  • 7[12]Camon P J, Symchych PS, Demmartion FE. The distribution of urate in human and primute kidney. Procsoc Exp Biol, 1968,129:278 - 284.
  • 8[13]Puig JG, Miranda M, Mateos FA. Hereditary nephrophropathy associated with hyperuricemia and gout.Arch Intern Med, 1993,153: 357 - 365.
  • 9[1]Emmerson BT,Cross M,Osborne JM,et al. Reaction of MDCK cell to crystals of monosodium urate monohydrate and uric acid. Kidney int, 1990,37(1) :36 - 43.
  • 10[2]Emmerson BT, Cross M, Osborne JM, et al. Ultrastructural studies of the reaction of urate crystals with a cultured renal tubular cell line. Nephron, 1991,59(3) :403 - 408.

共引文献3589

同被引文献618

引证文献83

二级引证文献1143

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部