基底动脉尖综合征12例分析

Top of the basilar artery syndrome:Report of 12 cases

目的:探讨基底动脉尖综合征的病因、临床表现、发病机制及影像学特征。方法:回顾分析12例基底动脉尖综合征病例的临床及影像学资料。结果:该病居前几位的症状和体征依次为意识障碍(75.0%)、眼球运动障碍(66.7%)、肢体活动障碍(58.3%)、眩晕(58.3%)和瞳孔改变(50.0%);栓塞和脑血栓形成是常见病因,危险因素为高血压(75.0%)、糖尿病(33.3%)、高血脂(25.0%)等;影像学表现以中脑、丘脑梗死(75.0%)多见,可合并颞叶(33.3%)、枕叶(41.7%)、小脑(41.7%)梗死。结论:基底动脉尖综合征临床及影像学表现复杂,常见病因和危险因素同一般脑卒中。头颅MRI检查有助于明确诊断。

Objective:To explore the etiology,clinical presentation,pathogenesis and imaging features in top of the basilar artery syndrome(TOBS ).Methods:The clinical and imaging data of 12 cases with TOBS were reviewed and analyzed.Results:Unconsciousness(75.0%),disturbance of eyeballs(66.7%),dyskinesia(58.3%),vertigo(58.3%),and abnormality of pupils (50.0%) were the most common symptoms and signs.The common etiology was embolism and cerebral thrombosis;the high risk factors were hypertension(75.0%),diabetes mellitus (33.3%),hyperlipemia(25.0%) and etc.;the imaging features in TOBS included infarction in midbrain and thalami(75.0%)and/or other sites,such as cerebellum(33.3%),occipital(41.7%),temporal lobes (41.7%)and so on.Conclusions:Complicated clinical manifestation and imaging features are often seen in TOBS.The etiology and high risk factors are similar to the cerebral stroke.Head MRI will help to accurate diagnosis.