化妆品中2-氯乙酰胺的气相色谱测定法

Determination of 2-Chloroacetamide in Cosmetic Products by Gas Chromatography boram

目的建立化妆品中2-氯乙酰胺的气相色谱测定法。方法样品用乙醇溶解,超声波均质,离心,经HP-INNWax色谱柱分离,氢焰离子化检测器检测。结果2-氯乙酰胺浓度在0.0～10.0mg/ml范围内时,该方法线性关系良好,检出限小于0.01μg,相对标准偏差小于5.6%,回收率为90%～100%。结论该方法简便、快速、灵敏,适用于化妆品中2-氯乙酰胺的测定。

Objective To establish a method for determination of 2-chloroacetamide in cosmetics. Methods The gas chromatography method had been developed for determination of 2-chloroacetamide in cosmetics. Samples were solved with ethanol treated with ultrasonic homogenization centrifuge separated by HP-INNWax column determined by FID. Results The 2-chloroacetamide concentration had a better linear range in the range of 0.0-10.0 mg/ml. The minimum detection limit was below 0.01 μg. The relative standard deviation was less than 5.6% and the recovery rates were 90%-100% respectively. Conclusion This method is simple fast and sensitive.