TUVP联合TURP治疗合并膀胱出口梗阻的前列腺癌

Combined Use of TUVP and TURP for Prostate Cancer with Bladder Outlet Obstruction

目的:探讨治疗合并膀胱出口梗阻前列腺癌的有效方法.方法:联合应用经尿道前列腺电汽化术(TU-VP)与经尿道前列腺电切术(TURP)治疗合并膀胱出口梗阻的前列腺癌患者47例,结合去势术及术后雄激素阻断治疗.结果:47例患者住院时间6～14 d,平均9.5 d;术后随访6～52个月.国际前列腺症状评分(IPSS)由术前的(26.5±4.8)分下降到(8.5±2.2)分(P＜0.05);最大尿流率(Qmax)从术前的(4.6±1.5)ml/s上升到(14.5±3.6)ml/s(P＜0.05);前列腺特异性抗原(PSA)从术前的(58.1±7.2)μg/L下降到术后3个月的(3.6±1.8)μg/L(P＜0.01).结论:联合应用TUVP与TURP,配合去势术及术后雄激素阻断是治疗合并膀胱出口梗阻前列腺癌的有效方法.

Objective: To investigate a new surgical method for the treatment of prostate cancer with bladder outlet obstruction.Methods: Forty-seven patients with prostate cancer complicated with bladder outlet obstruction were treated by combined use of transurethral electrovaporization ablation of the prostate (TUVP) and transurethral resection of the prostate (TURP).Results: The operations were successful, with satisfactory results and no serious complication. IPSS decreased from ((26.5)(4.8)) pre-operatively to ((8.5)(2.2)) post-operatively (P<(0.05)); Qmax increased from ((4.6)(1.5)) ml/s to ((14.5)(3.6)) ml/s (P<(0.05)); and PSA decreased from ((58.1)(7.2) ) μg/L to ((3.6)(1.8)) μg/L (P<(0.01)).Conclusion: The combined use of TUVP and TURP is a safe and ideal method for the treatment of prostate cancer with bladder outlet obstruction.