糖尿病糖化血红蛋白测定240例临床分析

Clinical analysis of 240 cases diabetes patients for determination of glycosylated hemoglobin

目的探讨黔南少数民族地区糖尿病糖化血红蛋白(GHb)测定的临床价值。方法240例住院糖尿病患者分为汉族组(144例),少数民族组(96例),采用氧化酶法测定受试患者空腹血糖(FBG)及餐后2小时血糖(2hPBG),使用亲和层析微柱法测定糖化血红蛋白Alc(GHbAlc)。结果受试患者GHbAlc与当天FBG及2hPBG比较有显著相关性(P<0.05),汉族组与少数民族组GHbAlc比较无明显差异(P>0.05)。结论本组实验结果提示,GHbAlc含量的检测有助于糖尿病的诊断和疗效观察,以及早期认识与预防糖尿病慢性并发症。

Objective To explore clinical efficacy of diabetes glycosylated hemoglobin(GHb) measurement in Qiannan minority nationality. Methods 240 cases of inpatients diabetes were separated into the Han nationality group(144) and minority nationality(96). Fasting blood glucose(FBG) and 2 hours post blood glucose(2hPBG) measurement were used by oxidase, GHbAlc measurement by micro column affinity chromatography hand-work method. Results There were significant relationship between GHbAlc and FBG?2hPBG(P<0.05). There were no obvious relationship between Han nationality group and minority nationality group in GHbAlc(P>0.05). Conclusions The present study has shown that GHbAlc guantity determination helps to further dignosis and treatment effects observation in diabetes, and early recognize and prevent chronic complication for diabetes.